Blog - INTERNET MÉDICA

Síndrome Metabólica: Mednews (Metabolic syndrome: Medical X Press)

Por Paulo Leite 16/05/2023

■ Arterial stiffness may cause metabolic syndrome in adolescentes via na increase in fasting insulin and LDL cholesterol

University of Eastern Finland – april 2023

https://medicalxpress.com/news/2023-04-arterial-stiffness-metabolic-syndrome-adolescents.html

■ Severe hot flashes after menopause increase metabolic syndrome risk in women, finds long-term study

European Society of Endocrinology – may 2023

https://medicalxpress.com/news/2023-05-severe-hot-menopause-metabolic-syndrome.html

■ Metabolic syndrome with heavy alcohol use contributes to recente surge in alcoholic liver disease-related mortality

American College of Physicians – may 2023

https://medicalxpress.com/news/2023-05-metabolic-syndrome-heavy-alcohol-contributes.html

■ Longer siestas linked to higher risk of obesity, metabolic syndroe and high blood pressure

Brigham and Women´s Hospital – april 2023

https://medicalxpress.com/news/2023-04-longer-siestas-linked-higher-obesity.html

■ Selenium as a predictor of metabolic syndrome in Middle-aged women

Impact Journals LLC – april 2023

https://medicalxpress.com/news/2023-04-selenium-predictor-metabolic-syndrome-middle-aged.html

■ Study attemts to identify bacterial indicator species of obesity and metabolic syndrome in adults and pediatric patients

International Association for Dental Research – march 2023

https://medicalxpress.com/news/2023-03-bacterial-indicator-species-obesity-metabolic.html

■ Q and A: Metabolic syndrome and lifestyle changes

Robert Rizza! Medical X Press – march 2023

https://medicalxpress.com/news/2023-03-metabolic-syndrome-lifestyle.html

■ Health-sector shift work linked to increased odds of metabolic syndrome

Medical X Press – july 2022

https://medicalxpress.com/news/2022-07-health-sector-shift-linked-odds-metabolic.html

■ Prevalence of metabolic syndrome 32 percent in psoriasis patients

Medical X Press – june 2022

https://medicalxpress.com/news/2022-06-prevalence-metabolic-syndrome-percent-psoriasis.html

■ Impact of metabolic syndrome on severity of COVID-19 illness

Mary Liebert, Inc – january 2022

https://medicalxpress.com/news/2022-01-impact-metabolic-syndrome-severity-covid-.html

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■ Médico Responsável: Dr Paulo Fernando Leite

CRMMG: 7026

Belo Horizonte/MG/Brasil

Email: pfleite1873@gmail.com

Maio 2023

Câncer Hepatocelular (Hepatocelular carcinoma) 2023

Por Paulo Leite 13/05/2023

– O carcinoma hepatocelular (CHC) é a forma mais comum de câncer hepático primário, a terceira causa de morte de etiologia neoplásica e um dos tipos de câncer mais letais no mundo.

– É um tumor maligno que geralmente aparece em pacientes cirróticos e está mais comumente associado à hepatite B, hepatite C e alcoolismo crônico. Mais recentemente, a obesidade tem sido reconhecida como um importante fator de risco para diversos tipos de câncer, inclusive o de fígado.

– O diagnóstico é efetuado através de tomografia computadorizada de abdome com contraste endovenoso, e a ressonância magnética pode auxiliar nos casos que não possam ser definidos pela tomografia.

– Quando diagnosticado em seus estágios iniciais, o carcinoma hepatocelular é potencialmente curável. O único tratamento potencialmente curativo para o carcinoma hepatocelular é a ressecção do tumor, seja ela realizada através de hepatectomia parcial ou de transplante. Infelizmente, apenas cerca de 15% dos carcinomas hepatocelulares são passíveis de tratamento cirúrgico.

■ Screening and interventions to prevent nonalcoholic fatty liver disease/nonalcoholic steatohepatis-associated hepatocelular carcinoma

Simona Cernea, Danusia Onișor

World J Gastroenterol. 2023 Jan 14; 29(2): 286–309

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846941/

■ Pathology of combined hepatocelular carcinoma-cholangiocarcinoma: an update

Florian Roßner, Bruno Valentin Sinn, David Horst

Cancers (Basel) 2023 Jan; 15(2): 494

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856551/

■ Immunotherapy for hepatocelular carcinoma: current status and future perspectives

Deepa S Mandlik, Satish K Mandlik, Heena B Choudhary

World J Gastroenterol. 2023 Feb 14; 29(6): 1054–1075

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950866/

■ Updating the clinical application of blood biomarkers and their algorithms in the diagnosis and surveillance of hepatocelular carcinoma: a critical review

Endrit Shahini, Giuseppe Pasculli, Antonio Giovanni Solimando et al

Int J Mol Sci. 2023 Mar; 24(5): 4286

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001986/

■ Electroporación irreversible: presente y futuro en el tratamento del carcinoma hepatocelular

Cano, David, Lasarte, Juan José and Vivas, Isabel

Anales Sis San Navarra, Dic 2022, vol.45, no.3

https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1137-66272022000300009&lng=es&nrm=iso

■ High values of liver stiffness play an importante role in stratifying the risk of hepatocelular carcinoma in cirrhotic hepatites C patients

G L Reinoso-Pereira, D C Paranaguá-Vezozzo, D F Mazo et al

Arquivos de Gastroenterologia 2022, vol 59 (2): 204-211

https://www.scielo.br/j/ag/a/SwZL6PNhSDQDS3P5dDN8Ttx/?lang=en

■ Mortality due to hepatocelular carcinoma associated with hepatites B and C viroses in the state of São Paulo, Brazil

D F Cavalcante, E M Garcia, N S O Farias et al

Revista Brasileira de Epidemiologia 2022, vol 25: e220004

https://www.scielo.br/j/rbepid/a/Vzw3d6rSVW7D9Ky5xWGDFJx/?lang=en

■ Predictors of early and late hepatocelular carcinoma recurrence

Riccardo Nevola, Rachele Ruocco, Livio Criscuolo et al

World J Gastroenterol. 2023 Feb 28; 29(8): 1243–1260

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011963/

■ Risk factors for hepatocelular carcinoma in patients with on-alcoholic fatty liver disease

L N Cavalcante, M G F Dezan, C L S L Paz, A C Lyra

Arquivos de Gastroenterologia 2022, vol 59 (4): 540-548

https://www.scielo.br/j/ag/a/yGBCFcDx9dC3SHLkYjxqBZJ/?lang=en

■ Gene expression and sérum biomarkers for diagnosis of hepatocelular carcinoma, cirrhosis and hepatites C

R Fernandes-Ferreira, G D Tenani, M A s Pinhel et al

Arquivos de Gastroenterologia 2022, vol 59 (3): 394-401

https://www.scielo.br/j/ag/a/4x7HJXKvNRfSSDBKVSdJFqs/?lang=en

■ An overview of hepatocelular carcinoma surveillance focussing on non-cirrhotic NAFLD patients: a challenge for Physicians

Annalisa Cespiati, Felice Cinque, Marica Meroni, et al

Biomedicines. 2023 Feb; 11(2): 586

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953185/

■ Radiological findings in non-surgical recurrent hepatocelular carcinoma: from locoregional treatments to immunotherapy

Davide Ippolito, Cesare Maino, Marco Gatti et al

World J Gastroenterol. 2023 Mar 21; 29(11): 1669–168

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107213/

■ Unresectable hepatocelular carcinoma: a review of new advances with focus on targeted therapy and immunotherapy

B F Far, D Rabie, P Hemati et al

Livers 2023, vol 3 (1)

https://www.mdpi.com/2673-4389/3/1/11

■ Primary malignant liver tumors: eight-year experience ina Pediatric hospital in Brazil: a cross-sectional study

L E Falqueto, P R Vilar, H G Campos et al

Revista do Colégio Brasileiro de Cirurgiões 2022, vol 49: e20223273

https://www.scielo.br/j/rcbc/a/4SmxcgjRkdVqnDQvJ8HHpcF/?lang=en

■ Indication for liver transplantation due to hepatocelular carcinoma: analysis of 1,706 procedures over the past decade in the state of Paraná

A C T de Freitas, F D S Espinoza, et al

ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) 2022, vol 35: e1701

https://www.scielo.br/j/abcd/a/RxsQqfFpNPCmRQBKTvFZkCx/?lang=en7

■ Management of hepatocelular carcinoma: SASL expert opinion statement

N Goossens, C Toso, M H Heim

Swiss Med Wkly 2020, vol 150: w20296

https://smw.ch/index.php/smw/article/view/2845

■ Carcinoma hepatoceular: epidemiologia, biologia, diagnóstico e terapias

M A Gomes, D G Priolli, J G Tralhão e M F Botelho

Rev Assoc Med Bras 2013, vol 59 (5)

https://www.scielo.br/j/ramb/a/kRJmYGTXMPmRv5PSMVrD85m/

■ Carcinoma hepatoceular – uma revisão bibliográfica

B L Vianna, J F G Muncinelli, E Garcia et al

Revista Médica da UFPR 2015, VOL 2 (4)

https://revistas.ufpr.br/revmedicaufpr/article/view/44264/pdf_17