Blog - INTERNET MÉDICA

Síndrome de Heiner Online (Heiner Syndrome)

Por Paulo Leite 29/02/2020

– A síndrome de Heiner é uma hipersensibilidade não mediada por IgE ao leite de vaca, que freqüentemente causa doença pulmonar em bebês e crianças pequenas. É uma síndrome de hipersensibilidade alimentar. Os pacientes geralmente apresentam sintomas de infecção crônica ou recorrente do trato respiratório superior ou inferior. Foi relatado que a síndrome de Heiner pode causar hemorragia pulmonar recorrente e é difícil diferenciar da entidade de hemossiderose pulmonar idiopática, outra doença com hemorragia pulmonar recorrente de etiologia desconhecida, geralmente ocorrendo nas crianças mais velhas. A respiração aguda é um problema raro na síndrome de Heiner, que geralmente apresenta sintomas e sinais de doença respiratória crônica.

■ Hematochezia in a child with Heiner syndrome

Liu XY, Huang XR, Zhang JW, Xiao YM, Zhang T.

Front Pediatr. 2020 Jan 28;7:551

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354653/

■ Heiner syndrome: an uncommon cause of failure to thrive

Ojuawo AB, Ojuawo OB, Aladesanmi AO et al

Malawi Med J. 2019 Sep;31(3):227-229

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895385/

■ A diferente clinical presentation of Heiner syndrome. The case of diffuse alveolar hemorrhage causing massive hemopytysis and hematemesis

Ayse Selcan Koc, Asena Sucu, Umit Celik

Respir Med Case Rep. 2019; 26: 206–208

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354653/

■ Frecuencia de reactividad cutânea hacia alérgenos alimentarios en pacientes alérgicos

H Camero-Martínez, A I López-García, D Rivero-Yeverino et al

Rev Alerg Mex 2017, vol 64 (3): 291-297

http://revistaalergia.mx/ojs/index.php/ram/article/view/280/467

■ Dr Paulo Fernando Leite

Cardiologia/Prevenção Cardiovascular

Estratificação de Risco Cardiovascular

Consultório: Rua Padre Rolim 815/sala 601

Tel: 33245518

CRMMG: 7026

Email: pfleite1873@gmail.com

Data: Fev 2020

Oncologia: Five Things to Know About Online (Oncology: Five Things to Know About)

Por Paulo Leite 28/02/2020

■ Bone health after diagnosis of breast cancer

S M Ruzyck, N A Nixon

CMAJ 2019, vol 191 (49): E1452

1 – Treatment of breast cancer may increase fracture risk

2 – Patients with breast cancer should be assessed for fracture risk using a validated tool

3 – Bone is the most common site of metástases for patients with breast cancer

4 – Bisphosphonates can reduce morbidity from boné metástases

5 – Bisphosphonates improve survival and prevent boné metastasis in postmenopausal women with early-stage breast câncer

https://www.cmaj.ca/content/190/49/E1452

■ Melanoma

R Micieli, K Pon

CMAJ 2019, VOL 191 (19): e535

1 – Sun exposure plays an importante role in melanoma pathogenesis

2 – Melanomas also occur on sites of minimal sun exposures

3 – The mitogen-activated protein kinase pathway is implicated and may be diagnostically challenging

4 – Off all melanomas, 10% are amelanotic or hypopigmented and may be diagnostically challenging

5 – Any lesions suspicious for melanoma should be referred to dermatology

https://www.cmaj.ca/content/191/19/E535

■ Diagnosing ovarian cancer

M Walker, Mara Sobel

CMAJ 2018, vol 190 (42): E125

1 – Early-stage ovarian câncer is difficult to diagnose because presenting symptoms are vague and nonspecific

2 – Transvaginal ultrasonography is the initial imaging modality for women with symptoms of ovarian câncer

3 – Serum tumours markers can be helpul when a complex ovarian cyst is identified

4 – The RMI II can be used in primary care identify women requiring urgente assessment

5 – Women with a Strong family history of breast, ovarian or colonj câncer should be referred to a genetic counsellor

https://www.cmaj.ca/content/190/42/E1259

■ Human papilomavírus vaccines

S J Ismail. S L Deeks

CMAJ 2017, vol 189 (38): E121

1 – Human papilomavírus (HPV) can lead to câncer

2 – HPV vacines can prevent câncer

3 – HPV vacines are safe

4 – Canada´s National Advisory Committee on immunization recommends use of HPV vacines for females and males

5 – HPV vaccination rates are suboptimal

https://www.cmaj.ca/content/189/38/E1212

■ Myelodysplastic syndrome

R A Wells, R Buckstein, J Removitz

CMAJ 2016, VOL 188 (10): 751

1 – Myelodysplastic syndrome is a disease ofolder adult and is becomming more common

2 – Myelodysplastic syndrome commonly presentes as fatigue

3 – Myelodysplastic syndrome should be in older patients with macrocytic anemia

4 – Patients with unexplained severe or progressive cytopenia should be referred toa hematologista

5 – Active treatment is available and improves outcomes in myelodysplastic syndrome

https://www.cmaj.ca/content/188/10/751