Blog - INTERNET MÉDICA

Tireoidite de Hashimoto: Casos Clínicos (Hashimoto´s Tireoiditis: Case Reports)

Por Paulo Leite 08/10/2021

– A tireoidite de Hashimoto (TH) é uma doença auto-imune na qual os anticorpos produzidos pelo organismo acabam atacando as células tireoidianas e as destruindo

– A tireoidite de Hashimoto (TH) é considerada principal causa de bócio e hipotireoidismo adquirido em crianças e adolescentes em áreas não endêmicas.

– A encefalopatia de Hashimoto é um condição clínica rara associada com a tireoidite de Hashimoto

■ Hashimoto´s thyroiditis following SARS-CoV-2

Rafael Silvestre Knack, Taliê Hanada, Renata Silvestre Knack, Kamilla Mayr

BMJ Case Rep.2021; vol 14(8): e244909

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8354276/

■ Manifestation of thyroid disease post COVID-19: report of Hashimoto thyroiditis, Graves disease, and subacute thyroiditis

Karen Feghali, Jacqueline Atallah, Catalina Norman

J Clin Transl Endocrinol Case Rep.2021 Dec; 2: 100094

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8387132/

■ A diffuse large B-cell thyroid lymphoma presented as a compressive goiter in a young woman with no evidence of Hashimoto´s thyroiditis

Ibtissem Oueslati, Hiba‐Allah Chatti, Meriem Yazidi et al

Clin Case Rep.2021, vol 9(7): e04436

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8271253/

■ Hashimoto encephalopathy in pediatrics: report of 3 cases

Anne-Marie D. Kaulfers, Samar K. Bhowmick

AACE Clin Case Rep.2021, vol 7(1): 40–42

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7924160/

■ Recurrent painful Hashimoto thyroiditis successfully treated by thyroidectomy

Carol Chiung-Hui Peng, Kashif M. Munir, Linda Song et al

AACE Clin Case Rep.2020, vol 6(1): e9–e13

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7279768/

■ Acute psychosis secondary to steroid responsive encephalopathy associated with autoimmune Hashimoto thyroiditis

Shahd I. Ibrahim, Alaa M. Khalafalla, Abeer S. Safan et al

Clin Case Rep 2021, vol 9(9): e04644

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8418675/

■ A case of oculocutaneous albinism in a patient with Hashimoto´s thyroiditis

Giovanni de Gennaro, Paolo Vitti, Michele Marinò

Eur Thyroid J.2019, vol 8(1): 56–58

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6381916/

■ A novel assessment and treatment approach to patients with Hashimoto´s encephalopathy

Kate Laycock, Abhijit Chaudhuri, Charlotte Fuller et al

Endocrinol Diabetes Metab Case Rep.2018; 2018: 17-0117

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5931230/

■ Chronic immune thrombocytopenia and Hashimoto´s hypothyroidism in an adolescent: presentation and implications

Judy Ibrahim, Mohammad Alashqar, Shamma Al Zaabi et al

Case Rep Pediatr.2021; 2021: 6649155

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7872745/

■ An unusual case of Hashimoto´s thyroiditis presenting as impending cardiac tamponade in a patient with acquired immune deficiency syndrome (AIDS)

Ryan B. Sinit, Janet H. Leung, Wayne S. Hwang, J. Susie Woo, David M. Aboulafia

Am J Case Rep.2021; vol 22: e929249-1–e929249-7

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8165493/

■ Hashimoto´s encephalopathy: a case report and a short revision of current literature

Paola Chiarello, Valentina Talarico, Angela Nicoletti et al

Acta Biomed.2020; vol 91(3): e2020087

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7717026/

■ Dr Paulo Fernando Leite

Cardiologia/Prevenção Cardiovascular

Consultório: Rua Padre Rolim 815/sala 601 – Belo Horizonte/MG/Brasil

Tel: 33245518

CRMMG: 7026

Email: pfleite1873@gmail.com

Blog Internet Médica – www.internetmedica.com.br

Data: outubro 2021

Hipercalcemia Associada ao Câncer: Casos Clínicos (Cancer Associated Hypercalcemia: Clinical Cases)

Por Paulo Leite 08/10/2021

– A hipercalcemia associada à malignidade é descrita em 10 a 20% dos pacientes com câncer em alguma etapa da doença, e significa mau prognóstico.

– A hipercalcemia é mais comum no carcinoma de células escamosas de pulmão, cabeça e pescoço, carcinoma de células renais, câncer de mama, mieloma múltiplo e linfoma

– A hipercalcemia associada ao câncer é, com frequência, devida à produção tumoral de peptídeos relacionados ao paratormônio (PTHrp), que se liga a receptores de PTH/PTHrp e estimula a reabsorção óssea e inibe a excreção renal de cálcio.

– Os sintomas relacionados ao sistema nervoso central predominam, tais como progressivo declínio da capacidade cognitiva, estupor e coma.

– As alterações na função renal (incapacidade de concentrar a urina acarretando poliúria) e no trato gastrointestinal (anorexia, náuseas e vômitos) corroboram para a desidratação e agravam a hipercalcemia.

– A hipercalcemia causada pelo câncer é comumente classificada em: 1) hipercalcemia osteolítica local, decorrente da intensa reabsorção óssea osteoclástica nas áreas em torno das células malignas na medula óssea; 2) hipercalcemia humoral maligna, causada pela secreção do peptídeo relacionado ao paratormônio (PTHrP) pela neoplasia maligna; 3) hiperparatireoidismo ectópico; 4) produção de 1,25 (OH)2 D pelo tumor.

O controle adequado da hipercalcemia é necessário para dar tempo de o paciente responder ao tratamento antineoplásico.

■ Hypercalcemia and unilateral ovarian mass in a young adult: a case report of small cell ovarian carcinoma

Gregor Vivod, Sebastjan Merlo, Nina Kovačevi

Am J Case Rep.2021; vol 22: e928959-1–e928959-6

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7849373/

■ Hypercalcemia of malignancy in a case of peripheral nerve sheath tumor: elucidating the roles of simultaneous mechanisms

Malini Ganesh, Sanford Bai

AACE Clin Case Rep.2020, vol 6(3): e135–e140

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7282278/

■ Hypercalcemic crisis caused by a parathyroid mass requiring thoracoscopic resection

Rachel C. Kim, Alexandra M. Roch, Thomas J. Birdas et al

AACE Clin Case Rep.2021, vol 7(4): 264–267

https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-019-1363-5

■ Hypercalcemia of malignancy: simultaneous elevation in parathyroid hormone-related peptide and 1,25 dihydroxyvitamin D in sarcoma

Dong Won Kim, Ann Miller, Andrew Li, et al

Naomi Hardy, Kristi D. Silver

https://www.aaceclinicalcasereports.com/article/S2376-0605(21)00003-1/pdf

■ Hypercalcemia of malignancy attributed to cosecretion of PTH and PTHRPP in lung adenocarcinoma

Jeffrey M. Kroopnick, Ubaldo Martinez-Outschoorn, Madalina Tuluc, Caroline S. Kim

AACE Clin Case Rep.2021, vol 7(3): 200–203

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8165115/

■ Case Report: unmasking hypercalcemia in patients with neuroendocrine neoplasm. Experience from six Italian referral centers

Elisa Giannetta, Franz Sesti, Roberta Modica et al

Front Endocrinol (Lausanne) 2021, vol 12: 665698

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8170398/

■ Hypercalcemia of malignancy in metastatic esophageal squamous cell carcinoma with simultaneous PTHrp and calcitriol overproduction: a case report with literature review

Runbo Song, Yadav Bijay, Sophia H. Rizk, Shanjin Cao

Ann Med Surg (Lond) 2021, vol 68: 102667

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8358632/

■ Primary hyperparathyroidism presenting as a brown tumor with hypercalcemia crisis in a second-trimester pregnant woman: a case report

Yun Xu, Yingying Yu

Medicine (Baltimore) 2021, vol 100(20): e25968.

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8137077/

■ Hypercalcemia in small lymphocytic lymphoma with an elevated parathyroid hormone-related peptide associated with early Richter transformation

Ashish Bains, Pedro Covas, Olga Timofeeva, Michael Bromberg

Case Rep Hematol.2021; 2021: 5525721

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8099529/

■ Hypercalcaemia, renal dysfunction, anaemia and bone lesions (CRAB) do not always represent multiple myeloma: diffuse large B cell lymphoma presenting with CRAB symptomas in a 69-year-old man

Hafez Mohammad Ammar Abdullah, Moataz Ellithi, Qazi Waqas et al

BMJ Case Rep.2019; vol 12(8): e229070.

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6685385/

■ Calcitriol-mediated hypercalcemia as an immune-related adverse event in a patient receiving nivolumab and ipilimumab for metastatic renal cell carcinoma, case report

Kai Johnson, Majd Issa, Anish Parikh, et al

BMC Urol.2021; vol 21: 51

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8017871/

■ Hypercalcemic crisis caused by a parathyroid mass requiring thoracoscopic resection

Rachel C. Kim, Alexandra M. Roch, Thomas J. Birdas, et al

AACE Clin Case Rep 2021, vol 7(4): 264–267

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8282530/

■ A woman with a 27-year history of hyperparathyroidism and hypercalcemia who was diagnosed with low-grade parathyroid carcinoma

Monika Kaszczewska, Michał Popow, Witold Chudziński et al

Am J Case Rep.2021; vol 22: e930301-1–e930301-8.

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7957837/

■ Hypercalcemia an exceptional complication in upper urinary tract urothelial carcinoma

Issam Jandou, Elmehdi Wichou, Adnane Ettanji, et al

J Surg Case Rep.2021, vol 2021(2): rjaa574

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7880700/

■ A case of humoral hypercalcemia of malignancy secondary to hepatocellular carcinoma with fulminant clinical course

Pamela Castro-Camero, Bumsoo Park, Amit Gupta, et al

Spartan Med Res J 2019; vol 4(1): 8983.

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7746133/

■ Water clear cell ectopic non-iatrogenic giant parathyroid in sternohyoid muscle with thyroid nodule and asymptomatic hypercalcemia due to primary hyperparathyroidism: case report and literature review

Walla Mohamed, Walid El Ansari, Mohamed S. Al Hassan et al

Int J Surg Case Rep.2021, vol 86: 106295

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8397889/

■ Hipercalcemia grave como forma de apresentação de leucemia linfoblástica aguda em crianças

Martins, Andreia Luís, Moniz, Marta, Nunes, Pedro Sampaio, Abadesso, Clara, Loureiro, Helena Cristina, Duarte, Ximo, Almeida, Helena Isabel

Revista Brasileira de Terapia Intensiva 2015, vol 27 (4): 402-405

https://www.scielo.br/j/rbti/a/4RRkbzMNgPhbyh33PYjxwxH/?lang=pt

■ Hypercalcemia of malignancy

K L Feldener, J Sarno

J Adv Pract Oncol 2018, vol 9 (5): 496-504

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6505545/

■ A hypercalcemia nas malignidades: aspectos clínicos, diagnósticos e terapêuticos