Blog - INTERNET MÉDICA

Infecção Ocular: Casos Clínicos Online (Ocular Infection: Case Reports)

Por Paulo Leite 29/11/2018

■ Corneal infections associated with sleeping in contact lenses – six cases, United States, 2015-2018

Jennifer R. Cope, Nuadum Muriel Konne, Deborah S. Jacobs et al

MMWR Morb Mortal Wkly Rep. 2018, vol 17; 67(32): 877–881

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095652/

■ Neurite óptica secundária a infecção pelo Chikungunya Vírus

Giacomin, Natalia Torres et al.

Rev. bras.oftalmol., Ago 2018, vol.77, no.4, p.222-224

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802018000400222&lng=en&nrm=iso

■ Recurrent chikungunya retinitis

Silvia Olivia Salceanu, Vasant Raman

BMJ Case Rep. 2018; 2018: bcr2017222864

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119402/

■ Ocular abnormalities in congenital Zika syndrome: a case report, and review of the literature

Jade Gieseke Guevara, Swati Agarwal-Sinha

J Med Case Rep. 2018; vol 12: 161

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994093/

■ Inner retinal vasculopathy in Zika virus disease

Mandeep S. Singh, Maria Carolina Marquezan, Revaz Omiadze et al

Am J Ophthalmol Case Rep. 2018 Jun; 10: 6–

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789128/

■ Optic neuropathy and congenital glaucoma associated with probable Zika virus infection in Venezuelan patients

Gustavo De Moraes, Michele Pettito, Juan B. Yepez et al

JMM Case Rep. 2018 May; 5(5): e005145

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994708/

■ Non-congenital severe ocular complications of Zika virus infection

Mussaret B. Zaidi, C. Gustavo De Moraes, Michele Petitto et al

JMM Case Rep. 2018, vol 5(6): e00515

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096927/

■ Psicofísica visual em caso de toxoplasmose ocular congênita

Vieira, Raissa Cerveira et al.

Rev. bras.oftalmol., Out 2018, vol.77, no.5, p.292-295

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802018000500292&lng=en&nrm=iso

■ Repeat intravitreal dexamethasone implant for refractory cystoid macular edema in syphilitic uveitis

Cassandra C. Lautredou, Joshua S. Hardin, John R. Chancellor et al

Case Rep Ophthalmol Med. 2018; 2018: 7419823

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836310/

■ Isolated presumed optic nerve gumma, a rare presentation of neurosyphilis

Nailyn Rasool, James A. Stefater, Dean Eliott, Dean M. Cestari

Am J Ophthalmol Case Rep. 2017 Jun; 6: 7–10

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722128/

■ Cytomegalovirus retinitis in primary immune deficiency disease

Jia Jeane Ngai, Ka Lung Chong, Shelina Oli Mohamed

Case Rep Ophthalmol Med. 2018; 2018: 8125806

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169215/

■ Retinite por citomegalovírus em paciente com síndrome de Good

Jorge, Leticia Pinto Coelho, Pereira, Carlos Eduardo Gonçalves and Jorge, Eduardo

Rev. bras.oftalmol., Jun 2018, vol.77, no.3, p.153-155

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802018000300153&lng=en&nrm=iso

■ Two cases of cytomegalovirus panuveitis in immunocompetent patients

Masato Sakai, Hiroshi Takase, Kenichi Namba et al

Am J Ophthalmol Case Rep. 2018 Jun; 10: 189–191

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956625/

■ Herpes zoster ophthalmicus: pre-eruption phase sine herpete

Rohini R. Sigireddi, Lance J. Lyons, Hilary A. Beaver, Andrew G. Lee

Am J Ophthalmol Case Rep. 2018 Jun; 10: 201–20

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854874/

■ Molecular diagnosis and ocular imaging of varicella zoster virus associated neuroretinitis

Rene Y. Choi, Andreas Lauer, James T. Rosenbaum

Am J Ophthalmol Case Rep. 2018 Sep; 11: 146–148

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072656/

■ Retinitis associated with double infection of Epstein-Barr virus and varicella-zoster virus: a case report

Tomohito Sato, Riki Kitamura, Toshikatsu Kaburaki, Masaru Takeuchi

Medicine (Baltimore) 2018, vol 97(31): e11663

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081094/

■ A case of ocular Kaposi´s sarcoma successfully treated with highly active antiretroviral therapy (HAART) combined with docetaxel

Chongfei Jin, Hamza Minhas, Amandeep Kaur et al

Am J Case Rep. 2018; vol 19: 1074–1077.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140454/

■ Pseudomonas aeruginosa-induced bilateral endophthalmitis after bilateral simultaneous cataract surgery: case report

Mota, Sergio Hernandez-Da.

Arq. Bras. Oftalmol., Aug 2018, vol.81, no.4, p.339-34

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492018000400339&lng=pt&nrm=iso&tlng=en

■ Tuberculous uveitis presenting as pigmented hypopyon – a case report

Sachin B. Shetty, Santhosh H. Devulapally, Sowmiya Murali, Jaydeep A. Walinjkar, Jyotirmay Biswas

Am J Ophthalmol Case Rep. 2017 Sep; 7: 1–3

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722182/

■ A novel clinical sign in intraocular tuberculosis: active chorioretinitis within chorioretinal atrophy

Avinash Pathengay, Bhavik Panchal, Himadri Choudhury et al

Am J Ophthalmol Case Rep. 2017 Sep; 7: 59–6

■ Case report of the family transmission of Streptococcus pyogenes orbital cellulitis

Christelle Doyon, Émilie Goodyear

Am J Ophthalmol Case Rep. 2017 Jun; 6: 52–54

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722126/

■ Recurrent optic neuritis as the only manifestation of chronic hepatitis B virus flare: a case report

Diana Curras-Martin, Natasha Campbell, Attiya Haroon, Mohammad A. Hossain, Arif Asif

J Med Case Rep. 2018; 12: 316

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192156/

■ Cryptococcal choroiditis in advanced AIDS with clinicopathologic

Christopher M. Aderman, Ian R. Gorovoy, Daniel L. Chao et al

Am J Ophthalmol Case Rep. 2018 Jun; 10: 51–54

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956675/

■ Orbital apex syndrome from bacterial sinusitis without orbital cellulitis

Margaret L. Pfeiffer, Helen A. Merritt, Lucy A. Bailey, Karina Richani, Margaret E. Phillips

Am J Ophthalmol Case Rep. 2018 Jun; 10: 84–86

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814374/

■ Nocardial scleritis: a case report and a suggested algorithm for disease management based on a literature review

Laura Pires da Cunha, Verena Juncal, Cecília Godoy Carvalhaes et al

Am J Ophthalmol Case Rep. 2018 Jun; 10: 1–5

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956651/

■ Disseminated Nocardiosis with retinal abscess in a patient treated for bullous pemphigoid

Sidharth Puri, Amir Hadayer, Andrea Breaux, Charles C. Barr

Am J Ophthalmol Case Rep. 2018 Jun; 10: 145–147

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956661/

■ Acute-onset endophthalmitis caused by Staphylococcus lugdunensis

Robert B. Garoon, Darlene Miller, Harry W. Flynn, Jr.

Am J Ophthalmol Case Rep. 2018 Mar; 9: 28–30

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786861/

■ A case of hypertrophic herpes simplex virus affecting the eyelid and cornea masqueranding as IgG4-related disease

Prachi Dua, Roman Shinder, Derek B. Laskar et al

Am J Ophthalmol Case Rep. 2018 Mar; 9: 68–7

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786855/

■ Varicella zoster virus-associatted chorioretinitis: a case report

Joo Yeon Kim, Ji Hwan Lee, Christopher Seungkyu Lee, Sung Chul Lee

BMC Ophthalmol. 2018; 18: 28

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800090/

■ Cysticercosis of the eye

Rebika Dhiman, Saranya Devi, Kavitha Duraipandi, Parijat Chandra, Murugesan Vanathi, Radhika Tandon, Seema Sen

Int J Ophthalmol. 2017; 10(8): 1319–1324

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554854/

■ Optic neuritis and chorioretinitis as ocular manifestations of borreliosis in Brazil: three cases reported

Rodrigues, Bárbara Emilly Matos et al.

Rev. bras.oftalmol., Oct 2017, vol.76, no.5, p.259-261

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802017000500259&lng=en&nrm=iso&tlng=en

■ Late-onset postoperative Mycobacterium haemophilum endophthalmitis masquerading as inflammatory uveitis: a case report

Warinyupa Pinitpuwadol, Sucheera Sarunket, Sutasinee Boonsopon et al

BMC Infect Dis. 2018; 18: 70

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804003/

■ Filamentous gram-negative bacteria masquerading as actinomycetes in infectious endophthalmitis: a review of three cases

Joveeta Joseph, Savitri Sharma, Vivek Pravin Dave

J Ophthalmic Inflamm Infect. 2018; 8: 15

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179972/

■ Clostridium perfringens panophthalmitis and orbital cellulitis: a case report

Ghita Guedira, Nabil Taright, Hélène Blin et al

BMC Ophthalmol. 2018; 18: 88

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892009/

■ Ocular basidiobolomycosis: a case report

Napaporn Tananuvat, Sumet Supalaset, Muanploy Niparugs et al

Case Rep Ophthalmol. 2018 May-Aug; 9(2): 315–321

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047539/

■ Ocular dirofilariasis: ophthalmic implication of climate change on vector-borne parasites

Joseph D. Boss, Gabriel Sosne, Asheesh Tewari

Am J Ophthalmol Case Rep. 2017 Sep; 7: 9–1

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722161/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687513/

■ Intravitreal Angiostrongylus cantonensis: first case report in South America

Andrade, Gabriel Costa de et al.

Arq. Bras. Oftalmol., Jan 2018, vol.81, no.1, p.63-65

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492018000100063&lng=pt&nrm=iso&tlng=en

■ Delayed-onset Candida parapsilosis cornea tunnel infection and endophthalmitis after cataract surgery: histopathology and clinical course

Sotiria Palioura, Nidhi Relhan, Ella Leung et al

Am J Ophthalmol Case Rep. 2018 Sep; 11: 109–114

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038826/

■ Severe Achromobacter xylosoxidans keratitis with deep corneal involvement

Benjamin Lee, Cindy X. Cai, Divya Srikumaran, Fasika A. Woreta

Am J Ophthalmol Case Rep. 2018 Sep; 11: 128–130

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031244/

■ Effectiveness of voriconazole and corneal cross-linking on Phialophora verrucosa keratitis: a case report

Marisa Taechajongjintana, Ngamjit Kasetsuwan, Usanee Reinprayoon et al

J Med Case Rep. 2018; 12: 225

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098831/

■ Orbital implant exposure after Acanthamoeba panophthalmitis

Meredith S. Baker, Amanda C. Maltry, Nasreen A. Syed, Richard C. Allen

Am J Ophthalmol Case Rep. 2018 Jun; 10: 48–50

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956657/

■ Fungal endophthalmitis caused by Zygomycetes after pharcoemulsification

F C Ferreira, C K Ishii, A A Kusabara et al

JCRS 2018, vol 6 (3): 43-46

https://www.jcrscasereports.com/article/S2214-1677(18)30009-7/fulltext

■ Common orbital infections – state of the art – Part I

Shirin Hamed-Azzam, Islam AlHashash, Daniel Briscoe et al

J Ophthalmic Vis Res. 2018 Apr-Jun; 13(2): 175–182. doi: 10.4103/jovr.jovr_199_17

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905312/

■ Rare orbital infections – state of the art – Part II

Shirin Hamed-Azzam, Islam AlHashash, Daniel Briscoe et al

J Ophthalmic Vis Res. 2018 Apr-Jun; 13(2): 183–190

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905312/

■ by Dr Paulo Fernando Leite

Cardiologia – Centro Médico Unimed BH

Rua Gonçalves Dias 202

Belo Horizonte/MG/Brasil

31 30033306 / 40204020

CRMMG: 7026

Email: pfleite1873@gmail.com

Síndrome de Conn – Hiperaldosteronismo Primário Online (Conn Syndrome – Primary Aldosteronism)

Por Paulo Leite 29/11/2018

¨Dentre as principais causas de hipertensão arterial secundária, despontam as afecções tumorais que acometem a glândula supra-renal, sejam localizadas no córtex – aldosteronismo primário (síndrome de Conn) e síndrome de Cushing – ou na medula glandular – feocromocitoma. Embora, em sua maioria, esses tumores sejam benignos, a ressecção cirúrgica, curativa em cerca de 80% a 90% dos casos. O hiperaldosteronismo primário (HAP) foi descrito em 1955 por Jerome Conn e constitui causa rara de hipertensão arterial. Caracteriza-se pela produção excessiva de aldosterona devido à hiperfunção autônoma do córtex da adrenal e, geralmente, é causado por adenoma. Cursa com hipocalemia e aumento da pressão arterial por hipervolemia. A excessiva e prolongada secreção que ocorre no hiperaldosteronismo primário pode aumentar o sódio corporal e diminuir as concentrações de potássio, causando alcalose, aumento do líquido intracelular e da pressão arterial. O diagnóstico laboratorial se dá com a confirmação de elevadas concentrações de aldosterona na presença baixos níveis de atividade da renina. A maioria dos pacientes com a síndrome de Conn tem hipertensão arterial. Esses pacientes sabidamente têm mais risco de acidentes vasculares encefálicos, insuficiência renal, infarto do miocárdio. Cinco subtipos de hiperaldosteronismo primário já foram descritos. O adenoma adrenal é a principal causa desta síndrome (82% a 92%), mas ela também pode se dever a neoplasia maligna e hiperplasia do córtex glandular. Os pacientes podem se apresentar de forma assintomática ou oligossintomática, com sintomas decorrentes do próprio quadro hipertensivo ou das complicações geradas pela hipocalemia (poliúria, noctúria, cãimbras musculares, fraqueza muscular excessiva, parestesias, tetania e até paralisias musculares). Caracteriza-se por hipertensão arterial, hipocalemia, excreção urinária excessiva de potássio e alcalose metabólica. A prevalência de hiperaldosteronismo primário (HAP) é estimada entre 0,005% a 2,20% até relatos mais recentes de 5% de todos os pacientes com hipertensão arterial. O diagnóstico de HAP é confirmado pela relação plasma aldosterona / renina, seguida pelo teste de supressão da aldosterona; estes devem ser realizados em a) pacientes com hipertensão e hipocalemia; b) pacientes com hipertensão resistente ao tratamento (uso de três anti-hipertensivos); c) hipertensão grave (≥ 160 mmHg sistólica ou ≥ 100 mmHg) diastólica; d) hipertensão e incidentaloma; e) hipertensão arterial em paciente jovem. A dosagem de aldosterona e renina plasmática deve ser feita entre oito e dez horas da manhã no ambulatório; a relação aldosterona / renina aumentada deve ser confirmada com um teste de supressão da aldosterona. A confirmação do diagnóstico exige a demonstração de que não ocorre a supressão da aldosterona por uma sobrecarga de sódio. O estudo de imagem de escolha é a tomografia computadorizada das glândulas supra-renais. A abordagem terapêutica do HAP é medicamentosa ou cirúrgica, dependendo do subtipo do diagnóstico. O tratamento farmacológico com espironolactona visa a normalização da pressão arterial e dos níveis de potássio sérico, diminuindo o risco operatório e permitindo a recuperação da zona glomerulosa contralateral, geralmente atrofiada. Nos casos de hiperplasia bilateral, o tratamento medicamentoso está indicado, com espironolactona e anti-hipertensivos. Os pacientes com adenoma de adrenal respondem à ressecção cirúrgica (adrenalectomia unilateral), assim como casos específicos de hiperplasia, através da adrenalectomia parcial ou subtotal, com controle da pressão arterial e dos níveis séricos de potásssio. Atualmente, a adrenalectomia videolaparoscópica tornou-se a opção técnica preferível para o tratamento de tumores funcionantes pequenos e médios da glândula adrenal¨

■ ¨Malignant¨ hypertension from hyperaldosteronism: a case report

Krishna Mohan Baradhi, Thao Tran, Penchala Swamy Mittadodla

Pan Afr Med J. 2018; 30: 10

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093592/

■ Progress in the management of primary aldosteronism

Ryo Morimoto, Kei Omata, Sadayoshi Ito, Fumitoshi Satoh

Am J Hypertens. 2018 Apr; 31(5): 522–531

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905601/

■ Clinical characteristics of aldosterone – and cortisol-coproducing adrenal adenoma in primary aldosteronism

Lu Tang, Xintao Li, Baojun Wang et al

Int J Endocrinol. 2018; 2018: 4920841

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889857/

■ Improved identification of secondary hypertension: use of a systematic protocol

Kotliar C, Obregón S, Koretzky M et al

Ann Transl Med. 2018 Aug;6(15):293.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123210/

■ Síndrome de Conn

Arellano Aguilar, Gregorio et al.

Acta méd. Grupo Ángeles, Feb 2017, vol.15, no.1, p.68-69.

http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1870-72032017000100068&lng=es&nrm=iso

■ Primary aldosteronism: a common cause of resistant hypertension

Gregory A. Kline, Ally P.H. Prebtani, Alexander A. Leung, Ernesto L. Schiffrin

CMAJ. 2017 Jun 5; 189(22): E773–E778

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461126/

■ Histopathological classification of cross-sectional image-negative hyperaldosteronism

Yuto Yamazaki, Yasuhiro Nakamura, Kei Omata et al

J Clin Endocrinol Metab. 2017 Apr 1; 102(4): 1182–1192

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460723/

■ Aldosterone/direct rennin concentration ratio as a screening test for primary aldosteronism: a meta-analysis

Xiyue Li, Richa Goswami, Shumin Yang, Qifu Li

J Renin Angiotensin Aldosterone Syst. 2016 Jul-Sep; 17(3): 1470320316657450

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843892/

■ Update in primary aldosteronism

M Stowasser

The Journal of Clinical Endocrinology & Metabolism 2015, vol 100 (1): 1-10

https://academic.oup.com/jcem/article/100/1/1/2812690

■ Endocrine hypertension: an overview on the current etiopathogenesis and management options

Reena M Thomas, Ewa Ruel, Prapimporn Ch Shantavasinkul, Leonor Corsino

World J Hypertens. 2015; 5(2): 14–27

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582789/

■ Approach to the surgical management of primary aldosteronism

Maurizio Iacobone, Marilisa Citton, Giovanni Viel, Gian Paolo Rossi, Donato Nitti

Gland Surg. 2015 Feb; 4(1): 69–81

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321055/

■ Management of hypertension in primary aldosteronism

Anna Aronova, Thomas J Fahey III, Rasa Zarnegar

World J Cardiol. 2014 May 26; 6(5): 227–233

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062125/

■ Bone and mineral metabolism in patients with primary aldosteronism

L Petramala, L Zinnamosca, A Settevendemmie et AL

International Journal of Endocrinology 2014, Article ID 836529, 6 pages

https://www.hindawi.com/journals/ije/2014/836529/

■ Overview of the genetic determinants of primary aldosteronism

Abdallah Al-Salameh, Régis Cohen, Rachel Desailloud

Appl Clin Genet. 2014; 7: 67–79.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012345/

■ Adrenal gland inclusions in patients treated with aldosterone antagonists (spironolactone/eplerone): incidence, morphology and ultrastructural findings

Kishan A Patel, Edward P Calomeni, Tibor Nadasdy, Debra L Zynger

Diagn Pathol. 2014; 9: 14

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261889/

■ Autoimmune mechanisms activating the angiotensin AT1 receptor in ¨primary¨ aldosteronism

D C Kem, H Li, C Velarde-Miranda et AL

The Journal of Clinical Endocrinology & Metabolism 2014, vol 99 (55)

https://academic.oup.com/jcem/article/99/5/1790/2537548

■ Aldosterone and the risk of hypertension

Vanessa Xanthakis, Ramachandran S. Vasan

Curr Hypertens Rep. 2013 Apr; 15(2): 102–107.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619380/

■ What is the best criterion for the interpretation of adrenal vein sample results in patients with primary hyperaldosteronism?

Richard Webb, Aarti Mathur, Richard Chang et al

Ann Surg Oncol. 2012 Jun; 19(6): 1881–1886

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034057/

■ Evolution features of hypertensive patients with primary aldosteronism – prospective study

V Chioncel, D Păun, B Amuzescu, C Sinescu

J Med Life. 2012 Sep 15; 5(3): 354–359

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465007/

■ Persistent hypertension after adrenalectomy for an aldosterone-producing adenoma: weight as a critical prognostic factor for aldosterone´s lasting effect on the cardiac and vascular systems

Yvette Carter, Madhuchhanda Roy, Rebecca S. Sippel, Herbert Chen

J Surg Res. 2012 Oct; 177(2): 241–247

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474851/

■ Adrenocortical causes of hypertension

A Moraitis, C Stratakis

International Journal of Hypertension 2011, Article ID 624691, 10 pages

https://www.hindawi.com/journals/ijhy/2011/624691/

■ Adrenalectomía parcial laparoscópica en hiperaldosteronismo primário

Castillo, O.A., Díaz, M. and Arellano, L

Actas Urol Esp, Feb 2011, vol.35, no.2, p.119-122

http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0210-48062011000200012&lng=es&nrm=iso

■ Primary hyperaldosteronism: a case of unilateral adrenal hyperplasia with contralateral incidentaloma

Sujit Vakkalanka, Andrew Zhao, Mohammed Samannodi

BMJ Case Rep. 2016; 2016: bcr2016216209

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956976/

■ Aldosterone-producing adenoma and other surgically correctable forms of primary aldosteronism

Laurence Amar, Pierre-François Plouin, Olivier Steichen

Orphanet J Rare Dis. 2010; 5: 9

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889888/

■ Progress in primary aldosteronism: present challenges and perspectives

E. Gomez-Sanchez, G. P. Rossi, F. Fallo, M. Mannelli

Horm Metab Res. 2010 Jun; 42(6): 374–38

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823770/

■ Cardiovascular and renal damage in primary aldosteronism: outcomes after treatment

L A Sechi, G Colussi, A Di Fabio, C Catena

Am J Hypertens 2010, vol 23 (12)

https://academic.oup.com/ajh/article/23/12/1253/179708

■ Hiperaldosteronismo primário: relato de dois casos

Accetta, Pietro et al.

Rev. Col. Bras. Cir., Ago 2010, vol.37, no.4, p.311-31

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912010000400015&lng=en&nrm=iso

■ The diagnosis and treatment of primary hyperaldosteronism in Germany – results on 555 patients from the German Conn Registry

C Schirpenbach, F Segmiller, M Bidlingmaier et al

Dtsch Arztebl Int 2009, vol 106 (1): 305-311

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689591/

■ Hypokalemia induced myopathy as first manifestation of primry hyperaldosteronism – an elderly patient with unilateral adrenal hyperplasia: a case report

Panagiotis Kotsaftis, Christos Savopoulos, Dimitrios Agapakis et al

Cases J. 2009; 2: 6813

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740078/

■ Tratamento cirúrgico da hipertensão arterial secundária com origem na glândula supra-renal.

Marques, Ruy Garcia and Sanjuliani, Antonio Felipe

Rev. Col. Bras. Cir., Dez 2006, vol.33, no.6, p.401-410

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912006000600014&lng=en&nrm=iso

■ Primary aldosteronism: actual epidemics or false alarm?

Gordon, Richard D.

Arq Bras Endocrinol Metab, Oct 2004, vol.48, no.5, p.666-673

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302004000500012&lng=en&nrm=iso&tlng=en

■ Adenoma de Conn: uma causa de hipertensão e hipocalemia