Blog - INTERNET MÉDICA

Hemofilia Online (Hemophilia)

Por Paulo Leite 19/09/2019

¨Hemofilias são doenças hematológicas que acarretam alterações no processo da coagulação, devido à deficiência de algum fator de coagulação. As causas da doença são genéticas e as hemofilias mais comuns são a hemofilia A (deficiência de fator VIII) e hemofilia B (deficiência de fator IX). O gênero masculino é o mais acometido, com pico de ocorrência entre 20 e 29 anos, sendo que o tipo A aparece com maior frequência. Em todo mundo, 6,9 milhões de pessoas apresentam algum distúrbio hemorrágico e, no Brasil, quase 11 mil pessoas possuíam diagnóstico de algum tipo de hemofilia em 2012. Em virtude das alterações do processo de coagulação, as hemorragias tornam-se as complicações mais frequentes no indivíduo hemofílico, podendo ser espontâneas ou secundárias a um trauma. Os portadores de hemofilia apresentam dor persistente, que varia de intensidades moderada a intensa. Nessa população, o quadro álgico pode ocasionar a ocorrência de complicações musculoesqueléticas, como restrição dos movimentos articulares, fibrose articular, contraturas, alterações da marcha e da força muscular, hemartroses, hemorragias tissulares e artrite hemofílica (AH). O diagnóstico é feito por meio dos exames que investigam a cascata de coagulação: tempo de protrombina (TP), índice internacional normalizado (INR) e tempo de tromboplastina parcial ativada (TTPa). No caso de afetar a via intrínseca da coagulação, o TP estará normal, mas o TTPa estará alargado. Para confirmar se a deficiência é do fator IX podemos dosá-lo¨

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■ Developing a new scoring scheme for the hemophilia Joint Health Score 2.1

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Res Pract Thromb Haemost. 2019 Jul; 3(3): 405–411

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■ Hemophilia trials in the twenty-first century: defining patient important outcomes

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■ Dr Paulo Fernando Leite

Cardiologia/Prevenção Cardiovascular

Estratificação de Risco Cardiovascular

Novo endereço:

Consultório: Rua Padre Rolim 815/sala 815

Tel: 33245518 (Consulta Particular/Unimed)

– Centro Médico Unimed BH/Contagem/Pedro I

Belo Horizonte/MG/Brasil

CRMMG: 7026

Email: pfleite1873@gmail.com

Doença Arterial Periférica Online (Peripheral Arterial Disease)

Por Paulo Leite 19/09/2019

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■ Current status of arterial revascularization for the treatment of critical limb ischemia in infrainguinal atherosclerotic disease

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■ Ultrasound-guided sympathetic block of the radial artery with botulinum toxin to treat vasospasm

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■ Validation of the vascular quality of life questionnaire – 6 for clinical use in patients with lower limb peripheral arterial disease

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■ Twenty-year predictors of peripheral arterial disease compared with coronary heart disease in the Scottish Heart Health Extended Cohort (SHHEC)

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■ Primary care screening for peripheral arterial disease: a cros-sectional observational study

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■ Multidisciplinary approach to the diagnosis and management of patients with peripheral arterial disease

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■ Diagnosis and treatment of peripheral arterial disease