Síndrome Metabólica Online (Metabolic Syndrome)
A sídrome metabólica (SM) é um distúrbio multifatorial representado por um conjunto de fatores de risco cardiovascular usualmente relacionados à deposição central de gordura e à resistência à insulina. Para diagnóstico da SM, o indivíduo deve apresentar a combinação de pelo menos três dos cinco componentes: circunferência abdominal elevada, hipertrigliceridemia, redução do HDL colesterol, hipertensão arterial sistêmica e hiperglicemia. A associação da SM com a doença cardiovascular eleva a mortalidade geral em aproximadamente 1,5 vezes e a cardiovascular em 2,5 vezes. A associação entre adiposidade abdominal e aterosclerose subclínica foi documentada em diferentes populações. O diagnóstico de síndrome metabólica requer a presença de três ou mais dos critérios abaixo mencionados:
– Obesidade abdominal: (circunferência abdominal > 94 cm – homens; e > 80 cm – mulheres)
-Triglicérides: > 150 mg/dL
– HDL-colesterol: < 40 mg/dL (homens) e < 50 mg/dL (mulheres)
– Pressão arterial sistólica: 130 mmHg ou tratamento para hipertensão arterial
– Pressão arterial diastólica: > 85 mmHg ou tratamento para hipertensão arterial
– glicemia de jejum: 100 mg/dL
■ Epidemiological study of metabolic syndrome in Brazilian soldiers.
Fortes, Marcos de Sá Rego et al.
Arch. Endocrinol. Metab., Aug 2019, vol.63, no.4, p.345-350
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972019000700345&lng=en&nrm=iso
■ Effects of a new approach of aerobic interval training on cardiac autonomic modulation and cardiovascular parameters of metabolic syndrome subjects
Vanzella, Laís Manata et al.
Arch. Endocrinol. Metab., Apr 2019, vol.63, no.2, p.148-156
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972019000200148&lng=en&nrm=iso
■ Indicadores de Adiposidade Abdominal e Espessura Médio-Intimal de Carótidas: Resultados do Estudo Longitudinal de Saúde do Adulto – ELSA-Brasil
Eickemberg, Michaela et al
Arq. Bras. Cardiol., Mar 2019, vol.112, no.3, p.220-227
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2019000300220&lng=pt&nrm=iso&tlng=pt (Portuguese)
■ Anthropometric measurements as a potential non-invasive alternative for the diagnosis of metabolic syndrome in adolescents.
Mastroeni, Silmara Salete de Barros Silva et al.
Arch. Endocrinol. Metab., Jan 2019, vol.63, no.1, p.30-3
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972019000100030&lng=en&nrm=iso
■ Physical activity, cardiorespiratory fitness, and the metabolic syndrome
Jonathan Myers, Peter Kokkinos, Eric Nyelin
Nutrients. 2019 Jul; 11(7): 1652
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683051/
■ Mechanisms underlying metabolic syndrome-related sarcopenia and possible therapeutic measures
María Esther Rubio-Ruiz, Verónica Guarner-Lans, Israel Pérez-Torres, María Elena Soto
Int J Mol Sci. 2019, vol 20(3): 647
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387003/
■ The liver in children with metabolic syndrome
Ebe D’Adamo, Valeria Castorani, Valerio Nobili
Front Endocrinol (Lausanne) 2019; 10: 514
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687849/
■ Serum uric acid to HDL-cholesterol ratio is a strong predictor of metabolic syndrome in type 2 diabetes mellitus
Kocak, M. Zahid et al.
Rev. Assoc. Med. Bras., Jan 2019, vol.65, no.1, p.9-15
■ Potential protective effect of oleanolic acid on the components of metabolic syndrome: a systematic review
Ángel Fernández-Aparicio, Jacqueline Schmidt-RioValle, Javier S. Perona et al
J Clin Med. 2019, vol 8(9): 1294
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780804/
■ The Prevalence of Metabolic Syndrome in the Different Phenotypes of Polycystic Ovarian Syndrome
Tavares, Aleide and Barros, Romualda Castro Rêgo
Rev. Bras. Ginecol. Obstet., Jan 2019, vol.41, no.1, p.37-43
■ Detection of metabolic syndrome burden in healthy young adults may enable timely introduction of disease prevention
Anja Šoštarič, Barbara Jenko, Nada Rotovnik Kozjek, et al
Arch Med Sci. 2019 Sep; 15(5): 1184–1194
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764305/
■ Practical guidance for interventions in adults with metabolic syndrome: diet and exercise vs changes in body composition
Enrique Albert Pérez, Marina Poveda González, Rosa María Martínez-Espinosa, Mariola D Molina Vila, Manuel Reig García-Galbis
Int J Environ Res Public Health. 2019, vol 16(18): 3481
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765968/
■ Evidências científicas sobre a associação entre burnout e síndrome metabólica: revisão integrativa
Merces, Magno Conceição das et al.
Acta paul. enferm., Ago 2019, vol.32, no.4, p.470-476
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-21002019000400470&lng=en&nrm=iso
■ Cardiovascular risk and obesity
C Cercato, F A Fonseca
Diabetol Metab Syndr 2019, vol 11: 74
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712750/
■ Metabolic syndrome components are associated with oxidative stress in overweight and obese patients
Morelli, Nayara Rampazzo et al.
Arch. Endocrinol. Metab., May 2018, vol.62, no.3, p.309-318
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972018000300309&lng=en&nrm=iso
■ Síndrome Metabólica e Resistência Insulínica pelo Homa-IR no Climatério
Fonseca, Érika Joseth Nogueira da Cruz et al
Int. J. Cardiovasc. Sci., May 2018, vol.31, no.3, p.201-208
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472018000300201&lng=en&nrm=iso&tlng=pt (portuguese)
■ Long-term weight loss and metabolic health in adults concerned with maintaining or losing weight: findings from NHANES
G Knell, Q Li, K P Gabriel, K Shuval
Mayo Clin Proc 2018 vol 93 (11): 1611-1616
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526934/
■ Poor sleep quality is associated with insulin resistance in postmenopausal women with and without metabolic syndrome
Christopher E. Kline, Martica H. Hall, Daniel J. Buysse, et al
Metab Syndr Relat Disord. 2018 May 1; 16(4): 183–189.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931175/
■ Diagnostic imaging in the management of patients with metabolic syndrome
Seo Rin Kim, Lilach O. Lerman
Transl Res. 2018 Apr; 194: 1–18
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839955/
■ Metabolic syndrome and psoriasis: a study in 97 patients.
Ferdinando, Lana Bassi et al.
Rev. Assoc. Med. Bras., Apr 2018, vol.64, no.4, p.368-373
■ Características Relacionadas à Síndrome Metabólica em Indivíduos com Hipertensão Controlada e Hipertensão Resistente.
Catharina, Arthur Santa et al
Arq. Bras. Cardiol., June 2018, vol.110, no.6, p.514-521
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018000600514&lng=pt&nrm=iso&tlng=pt (Portuguese)
■ Prevalência e Fatores Associados com a Síndrome Metabólica na População Adulta Brasileira: Pesquisa Nacional de Saúde – 2013
Ramires, Elyssia Karine Nunes Mendonça et a
Arq. Bras. Cardiol., May 2018, vol.110, no.5, p.455-466
■ Prevalência de Síndrome Metabólica e Escore de Risco de Framingham em Homens Vegetarianos e Onívoros Aparentemente Saudáveis
Navarro, Julio Cesar Acosta et al
Arq. Bras. Cardiol., May 2018, vol.110, no.5, p.430-437
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018000500430&lng=pt&nrm=iso&tlng=pt (portuguese)
■ Síndrome Metabólica e Resistência Insulínica pelo Homa-IR no Climatério
Fonseca, Érika Joseth Nogueira da Cruz et al
Int. J. Cardiovasc. Sci., May 2018, vol.31, no.3, p.201-208
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472018000300201&lng=pt&nrm=iso&tlng=pt (Portuguese)
■ The global epidemic of the metabolic syndrome
M G Saklayen
Curr Hypertens Rep 2018, vol 20 (2): 12
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866840/
■ Metabolic syndrome and the skin: a more than superficial association. Reviewing, the association between skin diseases and metabolic syndrome and a clinical decision algorithm for high risk patients
E C Stefanadi, G Dimitrakakes, C Antoniou et al
Diabetol Metab Syndr 2018, vol 10: 9
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822485/
■ Impact of self-reported fasting duration on lipid profile variability, cardiovascular risk stratification and metabolic syndrome diagnosis.
Janovsky, Carolina Castro Porto Silva et al.
Arch. Endocrinol. Metab., Mar 2018, vol.62, no.2, p.187-192
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972018000200187&lng=en&nrm=iso
■ Metabolic syndrome and masked hypertension among Africans Americans: The Jackson Heart Study
Lisandro D. Colantonio, D. Edmund Anstey, April P. Carson et al
J Clin Hypertens (Greenwich). 2017 Jun; 19(6): 592–600
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697142/
■ Establishing post mortem criteria for the metabolic syndrome: an autopsy based cross-sectional study
M R Christensen, A Bugge, M E Malik et al
Diabetol Metab Syndr 2018, vol 10: 36
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918842/
■ Lifestyle recommendations for the prevention and management of metabolic syndrome: an international panel recommendation
Pablo Pérez-Martínez, Dimitri P. Mikhailidis, Vasilios G. Athyros et al
Nutr Rev. 2017 May; 75(5): 307–326
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914407/
■ Preditores de síndrome metabólicac em idosos: uma revisão
C C de Oliveira, E D da Costa, A K C Roriz et al
International Journal of Cardiovascular Sciences 2017, vol 30 (4): 343-353
http://www.onlineijcs.org/sumario/30/pdf/v30n4a09.pdf
■ Predictor of 25-hydroxyvitamin D status among individuals with metabolic syndrome: a cross-sectional study
S L S Aquino, A T O da Cunha, H T Pereira et al
Diabetol Metab Syndr 2018, vol 10: 45
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987652/
■ Predictors of Metabolic Syndrome in the Elderly: A Review
Oliveira, Carolina Cunha de et al.
Int. J. Cardiovasc. Sci., Aug 2017, vol.30, no.4, p.343-353
■ Peripheral polyneuropathy in severely obese patients with metabolic syndrome but without diabetes: Association with low HDL-cholesterol.
Nienov, Otto Henrique et al.
Rev. Assoc. Med. Bras., Apr 2017, vol.63, no.4, p.324-331
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302017000400324&lng=pt&nrm=iso
■ Caracterização da variabilidade da frequência cardíaca em indivíduos com síndrome metabólica
Rodrigues, Jhennyfer Aline Lima et al.
Rev Bras Med Esporte, Maio 2017, vol.23, no.3, p.208-21
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-86922017000300208&lng=pt&nrm=iso
■ Relationships between adiponectin levels, the metabolic syndrome, and type 2 diabetes: a literature review.
Frankenberg, Anize Delfino von, Reis, André F. and Gerchman, Fernando
Arch. Endocrinol. Metab., Dec 2017, vol.61, no.6, p.614-622
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972017000600614&lng=en&nrm=iso
■ Systematic review of metabolic syndrome biomarkers: a panel for early detection, management, and risk stratification in the West Virginian population
K Srikanthan, A Feyh, H Visweshwaar et al
Int J Med Sci 2016, vol 13 (1); 25-38
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716817/
■ Dr Paulo Fernando Leite
Cardiologia/Prevenção Cardiovascular
Estratificação de Risco Cardiovascular
Consultório: Rua Padre Rolim 815/sala 601
Tel: 33245518
CRMMG: 7026
Email: pfleite1873@gmail.com
Data: nov 2019