¨Acroceratose paraneoplásica – começa com eritema violáceo acral das orelhas, do nariz, das mãos e dos pés. As lesões iniciais podem mostrar vesículas pequenas. À medida que progridem, as lesões tornam-se hiperceratóticas e psoriasiformes, principalmente nas mãos e nos pés. Paroníquia e distrofia ungueal são comuns. Mais tarde, a erupção pode tornar-se generalizada e as lesões faciais podem ser semelhantes à dermatite ou ao lúpus. A síndrome é mais comum nos homens e está associada ao carcinoma espinocelular do trato gastrointestinal superior. Esta condição de pele paraneoplásica geralmente precede um diagnóstico de câncer de dois a seis meses. O diagnóstico diferencial inclui a psoríase. Resistência aos tratamentos convencionais, incluindo os esteróides podem alertar os médicos para um tumor maligno subjacente. Na maioria dos casos, a melhora ocorre após o tratamento do tumor primário.¨
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by Dr Paulo Fernando Leite
Médico Cooperado Unimed BH – CRMMG: 7026
Cardiologia – Centro Médico Unimed BH
Belo Horizonte/Minas Gerais/Brasil
Email: pfleite1873@gmail.com