Sinal de Frank (What Steven Spilberg, Mel Gibson and Emperor Hadrian have in common?

– “O sinal de Frank é um vinco diagonal no lóbulo da orelha que corre para trás em um ângulo de 45 graus através do lóbulo até a borda posterior da aurícula e pode ser um preditor de doença arterial coronariana. Ele indica envelhecimento prematuro e perda de fibras elásticas dérmicas e vasculares (ver fotos nos artigos online)

■ What do Steven Spilberg, Mel Gibson and Emperor Hadrian have in common? Frank´s sign and the link with coronary artery disease

Vasiliki Tsampasian, Vassilios S Vassiliou, Natasha Corballis

Oxf Med Case Reports.2021, 2021(10): omab097

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8557473/

■ Frank´s sign: dermatological marker for coronary artery disease

Omer Ali Mohamed Ahmed Elawad, Ahmed Abdalazim Dafallah Albashir

Oxf Med Case Reports.2021, 2021(9): omab089

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8451276/

■ Diagonal earlobe crease (Frank´s sign) for diagnosis of coronary artery disease: a systematic review of diagnostic test accuracy studies

Krzysztof Więckowski, Tomasz Gallina, Andrzej Surdacki, Bernadeta Chyrchel

J Clin Med.2021 , vol 10(13): 2799

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8268092/