■ Bone health after diagnosis of breast cancer
S M Ruzyck, N A Nixon
CMAJ 2019, vol 191 (49): E1452
1 – Treatment of breast cancer may increase fracture risk
2 – Patients with breast cancer should be assessed for fracture risk using a validated tool
3 – Bone is the most common site of metástases for patients with breast cancer
4 – Bisphosphonates can reduce morbidity from boné metástases
5 – Bisphosphonates improve survival and prevent boné metastasis in postmenopausal women with early-stage breast câncer
https://www.cmaj.ca/content/190/49/E1452
■ Melanoma
R Micieli, K Pon
CMAJ 2019, VOL 191 (19): e535
1 – Sun exposure plays an importante role in melanoma pathogenesis
2 – Melanomas also occur on sites of minimal sun exposures
3 – The mitogen-activated protein kinase pathway is implicated and may be diagnostically challenging
4 – Off all melanomas, 10% are amelanotic or hypopigmented and may be diagnostically challenging
5 – Any lesions suspicious for melanoma should be referred to dermatology
https://www.cmaj.ca/content/191/19/E535
■ Diagnosing ovarian cancer
M Walker, Mara Sobel
CMAJ 2018, vol 190 (42): E125
1 – Early-stage ovarian câncer is difficult to diagnose because presenting symptoms are vague and nonspecific
2 – Transvaginal ultrasonography is the initial imaging modality for women with symptoms of ovarian câncer
3 – Serum tumours markers can be helpul when a complex ovarian cyst is identified
4 – The RMI II can be used in primary care identify women requiring urgente assessment
5 – Women with a Strong family history of breast, ovarian or colonj câncer should be referred to a genetic counsellor
https://www.cmaj.ca/content/190/42/E1259
■ Human papilomavírus vaccines
S J Ismail. S L Deeks
CMAJ 2017, vol 189 (38): E121
1 – Human papilomavírus (HPV) can lead to câncer
2 – HPV vacines can prevent câncer
3 – HPV vacines are safe
4 – Canada´s National Advisory Committee on immunization recommends use of HPV vacines for females and males
5 – HPV vaccination rates are suboptimal
https://www.cmaj.ca/content/189/38/E1212
■ Myelodysplastic syndrome
R A Wells, R Buckstein, J Removitz
CMAJ 2016, VOL 188 (10): 751
1 – Myelodysplastic syndrome is a disease ofolder adult and is becomming more common
2 – Myelodysplastic syndrome commonly presentes as fatigue
3 – Myelodysplastic syndrome should be in older patients with macrocytic anemia
4 – Patients with unexplained severe or progressive cytopenia should be referred toa hematologista
5 – Active treatment is available and improves outcomes in myelodysplastic syndrome
https://www.cmaj.ca/content/188/10/751
■ Dr Paulo Fernando Leite
Cardiologia/Prevenção Cardiovascular
Estratificação de Risco Cardiovascular
Consultório: Rua Padre Rolim 815/sala 601
Tel: 33245518
CRMMG: 7026
Email: pfleite1873@gmail.com
Data: Fev 2020