■ Inflammatory bowel disease in children and adolescentes
N Chanchlani, R K Russel
CMAJ 2019, vol 191 (6): E164
1 – Diagnostic delay is common in pediatric inflamm3 atory bowel disease
2 – Extraintestinal manifestation of pediatric inflammatory bowel disease can occur before diagnosis
3 – The presence of perianal disease can be a highly specific finding when Crohn disease is suspected
4 – Once infection has been excluded, investigation of nonbloody diarrhea lasting longer than 2 weeks should be started in primary care
5 – Fecal calprotectin testing cana id in the diagnosis, as high levels indicated intestinal mucosa inflammation
https://www.cmaj.ca/content/191/6/E164
■ Reactivation of hepatites B vírus associated with immunosuppression therapy
J G H Lee, M Carruthers, H H Ko
CMAJ 2019, vol 191 (43): 2884
1 – Individuals with past hepatites B vírus (HBC) infection on immunosuppressive therapy are at risk of HBC reactivation
2 – Reactivation of HBV associated with immunosuppression therapy is a preventable cause of morbidity and mortality
3 – Onset of HBC reactiviation is variable
4 – Multiple factors play a role in the risk of HBV reactivation with immunosupression therapy
5 – Prophylactic antiviral therapy should be considered for those who are at moderate or high risk of HBV reactivation
https://www.cmaj.ca/content/190/43/E1284
■ Anal fissures
M A Dykstra, W Donald Buie
CMAJ 2019, vol 191 (26): E737
1 – Anal fissure may be acute or chronic
2 – Fissures that are off midline require further investigation
3 – Most fissures will resolve with conservative or medical management
4 – Topical calcium channel blockers are recommended as first line medical therapy for chronic fissures
5 – The presence of fissure should not preclude investigation of rectal bleeding for patients at higher risk
https://www.cmaj.ca/content/191/26/E737
■ Gastroenterologia: Five Things to Know About Online (Gastroenterology: Five Things to Know About)
■ Dr Paulo Fernando Leite
Cardiologia/Prevenção Cardiovascular
Estratificação de Risco Cardiovascular
Consultório: Rua Padre Rolim 815/sala 601
Tel: 33245518
CRMMG: 7026
Email: pfleite1873@gmail.com
Data: Fev 2020