Coagulopathy associated with COVID-19

1 – About 20%-55% of patients admitted to hospital for coronavirus disease 2019 (COVID-19) have laboratory evidence of coagulopathy

2 – COVID-19-associated coagulopathy appears to be prothrombotic

3 – Elevated d-dimer concentration is associated with poor clinical outcomes

4 – In the absence of a contraindication, patients admitted to hospital should receive venous thromboembolism prophylaxis as per standard of care

5 – Transfusion of blood products should be avoided in patients who do not have active, major bleeding

 

Five things to know about: Coagulopathy associated with COVID-19

S G Lee, M Fralick, M Sholzberg

CMAJ 2020, VOL 192 (21): e583

https://www.cmaj.ca/content/192/21/E583

 

Abnormal hemostatic parameters and risk of thromboembolism among patients with COVID-19 infection

R Castelli, A Gidaro

J Hematol 2020, vol 9 (1-2): 1-4

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188381/

 

Treatment of patients with nonsevere and severe coronavirus disease 2019: an evidence-based guideline

Z Ye, B Rochwerg, Y Wang et al

CMAJ 2020, vol 192 (20): E536-E545

https://www.cmaj.ca/content/192/20/E536

 

Safety considerations with chroloquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection

D N Juurlink

CMAJ 2020, vol 192 (17): E450-E453

https://www.cmaj.ca/content/192/17/E450

 

■  Dr Paulo Fernando Leite

Cardiologia/Prevenção Cardiovascular

Estratificação de Risco Cardiovascular

Consultório: Rua Padre Rolim 815/sala 601 – Belo Horizonte/MG/Brasil

Tel: 33245518

CRMMG: 7026

Email: pfleite1873@gmail.com

Data: junho 2020