Hipertireoidismo: Sinais & Sintomas Online (Hyperthyroidism: Signs & Symptoms)

Sintomas

– Aumento do apetite

– Aumento da frequência de defecações, diarréia

– Ansiedade, hiperatividade, nervosismo

– Intolerância ao calor

– Dispnéia

– Distúrbios do sono, insônia

– Fadiga, letargia

– Intolerância a exercícios

– Oligomenorréia, amenorréia

– Palpitações

– Perda de peso associada a aumento do apetite

– Perda do libido, disfunção erétil

– Queixas oculares

Sinais

– Arritmia (atriais), taquicardia, fibrilação atrial

– Agitação, psicose

– Aumento da sudorese

– Baqueteamento digital

– Bócio

– Eritema palmar

– Fraqueza musculara proximal

– Ginecomastia

– Insuficiência cardíaca de alto débito

– Oligomenorréia, amenorréia

– Oftalmopatia de Graves

– Paralisia periódica

– Pele quente e úmida

– Perda de cabelo

– Precórdio hiperdinâmico

– Sopro sobre a tireóide

– Tremor fino, hyperreflexia

– Unhas quebradiças

Crise Tireotóxica

– É uma exacerbação dramática, com risco de vida, do hipertireoidismo (tireotoxicose). É o extremo de um continuum de gravidade do hipertireiodismo, que está associado a uma elevada taxa de mortalidade de 20% se não tratado. É um diagnóstico clínico, baseado na gravidade do hipertireoidismo.

■ Hyperthyroidism

Amanda R. Doubleday, Rebecca S. Sippel

Gland Surg. 2020 Feb; 9(1): 124–135

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082267/

■ A case of unilateral dermopathy possibly related to Grave´s disease

C Rodia, F Menconi, L Mazoni et al

Eur Thyroid J 2020, vol 9 (1): 25-31

https://www.karger.com/Article/FullText/500297

■ National trends in incidence, mortality, and clinical outcomes of patients hospitalized for thyrotoxicosis with and without thyroid storm in the United States, 2004-2013

Rodolfo J. Galindo, Carolina R. Hurtado, Francisco J. Pasquel et al

Thyroid. 2019 Jan 1; 29(1): 36–43.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916241/

■ Management of thyrotoxicosis in children and adolescents: a Turkish Multi-center experience

İhsan Esen, Elvan Bayramoğlu, Melek Yıldız et al

J Clin Res Pediatr Endocrinol. 2019 Jun; 11(2): 164–172

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571539/

■ The incidence of childhood thyroxicosis is increasing in both girls and boys in Sweden

Maria Rodanaki, Maria Lodefalk, Katharina Forssell, et al

Horm Res Paediatr. 2019 Jul; 91(3): 195–202

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690413/

■ Hyperthyroidism in the pregnant woman: maternal and fetal aspects

Mariacarla Moleti, Maria Di Mauro, Giacomo Sturniolo et al

J Clin Transl Endocrinol. 2019 Jun; 16: 100190

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484219/

■ Association of radioactive iodine treatment with cancer mortality in patients with hyperthyroidism

C M Kitahara, A B de Gonzalez, A Bouville et al

JAMA Intern Med 2019, vol 179 (8): 1034-1042

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2737319

■ Long-term outcome of thyrotoxicosis in childhood and adolescence in the west of Scotland: the case for long-term antithyroid treatment and the importance of initial counselling

Mariam Kourime, Sheena McGowan, Mabrouka Al Towati, et al

Arch Dis Child. 2018 Jul; 103(7): 637–642

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047164/

■ Echocardiographic evolution of pulmonary hypertension in female patients with hyperthyroidism

Cristina Tudoran, Mariana Tudoran, Mihaela Vlad, et al

Anatol J Cardiol. 2018 Sep; 20(3): 174–181

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237944/

■ Hyperthyroidism in a complete molar pregnancy with a mature cystic ovarian teratoma

Bryce C. Simes, Alozie A. Mbanaso, Carlos A. Zapata, Chukwuma M. Okoroji

Thyroid Res. 2018; 11: 12

https://thyroidresearchjournal.biomedcentral.com/articles/10.1186/s13044-018-0056-7

■ Severe Mitral Regurgitation by Hyperthyroidism in the Absence of Left Ventricular Dilatation

Jorge, Antonio José Lagoeiro et al

Int. J. Cardiovasc. Sci., Apr 2018, vol.31, no.2, p.190-19

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472018000200190&lng=pt&nrm=iso

■ Grave´s hyperthyroidism in pregnancy: a clinical review

Caroline T. Nguyen, Elizabeth B. Sasso, Lorayne Barton, Jorge H. Mestman

Clin Diabetes Endocrinol. 2018; 4: 4.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831855/

■ ECG changes in patients with primary hyperthyroidism

Ishtiaque Hussain Baladi, Ayesha Aslam Rai, Syed Masroor Ahmed

Pan Afr Med J. 2018; 30: 246

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307920/

■ 2018 European Thyroid Association guideline for the management of Grave´s hyperthyroidism

George J. Kahaly, Luigi Bartalena, Lazlo Het al

Eur Thyroid J. 2018 Aug; 7(4): 167–186

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140607/

■ Amiodarone-induced thyrotoxicosis with cardiopulmonary arrest

Kosuke Inoue, Jun Saito, Tetsuo Kondo, et al

Intern Med. 2018 Jan 1; 57(1): 59–63

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799058/

■ Clinical feasibility of monitoring resting heart rate using a wearable activity tracker in patients with thyrotoxicosis: prospective longitudinal observational study

Jie-Eun Lee, D H Lee, T J Oh et al

JMIR Mhealth Uhealth. 2018 Jul; 6(7): e159

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064040/

■ Thyrotoxic periodic paralysis: an unusual presentation of hyperthyroidism

M Salih, C M J van Kinschot, R P Peeters et al

The Netherland Journal of Medicine 2017, vol 75 (8)

http://www.njmonline.nl/getpdf.php?id=1893

■ Thyrotoxicosis – investigation and management

Jackie Gilbert

Clin Med (Lond) 2017 Jun; 17(3): 274–277

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297572/

■ Hyperthyroidism and the heart

Patricia Mejia Osuna, Maja Udovcic, Morali D. Sharma

Methodist Debakey Cardiovasc J. 2017 Apr-Jun; 13(2): 60–63

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512680/

■ Caracterización de pacientes controlados por enfermedad de Basedow Graves en un hospital universitário

Lanas, Alejandra et al.

Rev. méd. Chile, Abr 2017, vol.145, no.4, p.436-440

https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000400003&lng=en&nrm=iso

■ Tiroides ectópica dual hiperfuncionante: Abordaje quirúrgico dual.

Salazar O, Alejandro et al.

Rev. Otorrinolaringol. Cir. Cabeza Cuello, Mar 2018, vol.78, no.1, p.110-120

https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0718-48162018000100110&lng=es&nrm=iso&tlng=es

■ Radioyodo como tratamiento de hipertiroidismo en un paciente en hemodiálisis: Caso clínico.

Hurtado, Claudia et al.

Rev. méd. Chile, Mayo 2017, vol.145, no.5, p.673-677

https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0034-98872017000500017&lng=en&nrm=iso

■ Hyperthyroidism

Simone De Leo, Sun Y Lee, Lewis E Braverman

Lancet. 2016 Aug 27; 388(10047): 906–918

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014602/

■ Managing hyperthyroidism in pregnancy: current perspectives

Stine Linding Andersen, Peter Laurberg

Int J Womens Health. 2016; 8: 497–504

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034921/

■ Preditores de Recorrência de Fibrilação Atrial em Pacientes com Eutireoidismo e Hipertireoidismo

Gürdoğan, Muhammet et al.

Arq. Bras. Cardiol., Feb 2016, vol.106, no.2, p.84-91

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016000200084&lng=en&nrm=iso&tlng=pt (portuguese)

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016000200084&lng=en&nrm=iso&tlng=en

(english)

■ A combination of tachycardia-mediated heart failure and coronary artery vasospasm-induced silent myocardial infarction in a patient with severe thyrotoxicosis

Serena Sert Kim Khoo, Chong Mow Chu, Yin Khet Fung

Case Rep Cardiol. 2018; 2018: 4827907

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866855/

■ Clinical and therapeutic controversies on subclinical hyperthyroidism

Salles, Fernanda and Salles, Daniela

MedicalExpress (São Paulo, online), Oct 2014, vol.1, no.5, p.251-256

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2358-04292014000500251&lng=pt&nrm=iso&tlng=en

■ Consenso brasileiro para o diagnóstico e tratamento do hipertireoidismo: recomendações do Departamento de Tireoide da Sociedade Brasileira de Endocrinologia e Metabologia

Maia, Ana Luiza et al.

Arq Bras Endocrinol Metab, Abr 2013, vol.57, no.3, p.205-232

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302013000300006&lng=en&nrm=iso

■ Oftalmopatia de Graves Online (Graves Ophthamopathy)

Arquivo – julho 2019

https://internetmedica.com.br/oftalmopatia-de-graves-online-graves-ophthalmopathy/

■ Doença da Tireóide: Mednews Online (Thyroid Disease: Guidelines)

Arquivo – Agosto 2019

https://internetmedica.com.br/doenca-da-tireoide-mednews-online-thyroid-disease-mednews/

■ Tireoidectomia Online (Thyroidectomy)

Arquivo – novembro 2018

https://internetmedica.com.br/tireoidectomia-online-thyroidectomy/